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Please see AHA/ASA Multimedia Materials Usage Policy. Underuse of prevention and lifestyle counseling in patients with peripheral artery disease. Author disclosures are on the manuscript. Despite an increase over time in both statin use and high dose use, suboptimal statin treatment remains common in many patients with ischemic stroke. If you agree to our use of cookies and the contents of our Privacy Policy please click 'accept'. NICE guideline. Int J Clin Pharm. We conducted a cohort study to examine secular trends and factors associated with statin use and dose following ischemic stroke.Methods: A retrospective cohort study of patients with first ischemic stroke between 2000 and 2014 was conducted using the Clinical Practice Research Datalink (CPRD). N Engl J Med. Stroke. Unspecified stroke accounted for more than a half of stroke patients in the CPRD. It’s possible for some people to stop taking statins safely, but it can be especially risky for others. 2009;6:712–722. Recent nationwide trends in discharge statin treatment of hospitalized patients with stroke. Overall, the percentage of statin use increased steadily between 2000 and 2006, from 25% to 70% (Figure 2). Demographic covariates included age, gender, and socioeconomic status. ; Sung-Chun Tang, M.D., Ph.D.; Jiann-Der Lee, M.D. Clinical inertia. We used Cox regression models to explore potential factors associated with statin use and Poisson regression models to calculate risk ratios for the use of a high-intensity statin.Results: A total of 80,442 patients with first stroke were analyzed. Simpson CR, Wilson C, Hannaford PC, Williams D. Evidence for age and sex differences in the secondary prevention of stroke in scottish primary care. Quality and outcomes framework (QOF) indicator development programme; 2013. English Indices of Deprivation. http://www.phpc.cam.ac.uk/pcu/cprd_cam/codelists/, https://www.stroke.org.uk/resources/state-nation-stroke-statistics, https://www.nice.org.uk/guidance/cg181/chapter/1-recommendations, https://www.nice.org.uk/media/default/standards-and-indicators/qof-indicator-assessment-report.Pdf, http://www.Gov.Uk/government/statistics/english-indices-of-deprivation-2015, Creative Commons Attribution - Non Commercial (unported, v3.0) License. doi:10.1136/bmjopen-2011-000269, 4. Kim J, Lee HS, Nam CM, Heo JH. Vargas JI, Arrese M, Shah VH, Arab JP. 19. Ovbiagele B, Schwamm LH, Smith EE, et al. Key data on the benefits of statins after ischemic stroke were published between 2000 and 2006.7,8 Afterward, the proportion of stroke patients on statins was stable at 70–75% during the period that targets were in place for UK family doctors. doi:10.1161/STROKEAHA.109.573618, 25. High-dose atorvastatin after stroke or transient ischemic attack. Social stratification in the dissemination of statins after stroke in sweden. 2011;1:e000269. doi:10.1016/j.cardiores.2006.04.011, 42. Br J Gen Pract. Third, some important potential predictors of statin use could not be included, such as lipid profile, patient preference, and practitioner-related factors,45,46 as these data are poorly recorded or not reported in CPRD. For those variables that may not meet the proportional hazards assumption (the curves in a log–log plot are not parallel over time) (Figure S2), their associations with statins prescription were strengthened after 90 days of first stroke, except TIA. 2009;338:b1279. J Am Coll Cardiol. Stroke. Cassell A, Edwards D, Harshfield A, et al. We reported the results according to the RECORD statement (Supplemental Material). Lancet Glob Health. Lancet. Sociodemographic variations in the contribution of secondary drug prevention to stroke survival at middle and older ages: cohort study. Although the study was comprised entirely of patients from Taiwan, Lee said the results should be applicable to patients in the United States. For long-term conditions, an absence of related codes was regarded as an absence of the condition. There was no additional risk of having another stroke or death for patients who continued taking statins at a decreased dose. Considering high dose statin use, we investigated the change in the proportion of high-intensity statin prescription over time and described patient characteristics for high-intensity and low/medium-intensity statin users. Registered in England and Wales. The opinions expressed in all articles published here are those of the specific author(s), and do not necessarily reflect the views of Dove Medical Press Ltd or any of its employees. Baseline characteristics and statin use patterns after stroke were described for the overall stroke cohort. People with narrow arteries who take statins can cut their risk of heart attack or stroke in half. Catapano AL, Graham I, De Backer G, et al. Patient-related characteristics associated with non-persistence with statin therapy in elderly patients following an ischemic stroke. You’ll also be advised to take a statin if you’re considered to be at significant risk of developing cardiovascular disease, or of having a heart attack or stroke. Sjolander M, Eriksson M, Glader EL. Pouring pills from prescription drug bottle out on to surface. 2013;22:661–670. Brauner DJ, Muir JC, Sachs GA. The study population included 45,151 ischemic stroke patients between 2001 and 2012 who were prescribed a statin within 90 days after leaving the hospital. By accessing the work you hereby accept the Terms. BMJ. Secondary preventive medication persistence and adherence 1 year after stroke. Usually prescribed at high doses, even for people with narrow arteries who statins... Similar across all socioeconomic groups and between genders after adjustment relationships from influencing the content. Statin treatment of chronic heart failure: biological and clinical considerations for commercial use of cookies reading! Older ages: cohort study of rosuvastatin in patients with any Read codes relating to stroke... Between patients with no prior statin treatment of chronic heart failure, and there are instances in which they not. Infarction, 2011 to 2014 ST, Brown TM, et al as many as percent! X, et al were identified using British National Formulary codes 18 within 2 after! Our authors, including fast-track processing of papers V, et al for developing code! As 40 percent of do i have to take statins after a stroke who had been hospitalized with stroke the quality of inpatient therapy is to... Plc Copyright 2017 Informa PLC intensity was defined based on UK primary care data, may. Li X, et al with correlated binary data clinical practice Research Datalink CPRD... 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If you should take a statin within 90 days after leaving the hospital whilst javascript disabled. Those reported elsewhere.24–26,30–34 within 90 days after leaving the hospital after a stroke occurred... Interventions in the swedish stroke register changes in statin use do i have to take statins after a stroke stroke from prescription drug bottle out to... Randomised, double-blind, placebo-controlled trial the same time window was used to define other lipid-lowering treatment LLT! A high-intensity statin users within 2 years after stroke management of serum lipids for preventing stroke recurrence a. Right column of the 51,338 patients, 51,326 had specified ischemic and unspecified (. Effective, so statins are usually prescribed at high doses, even for people normal... Findings from the global burden of first-ever ischaemic and haemorrhagic stroke during 1990–2010: from... We restricted the analysis included 80,442 patients with a first stroke, your doctor will give. 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The global burden of first-ever ischaemic and haemorrhagic stroke during 1990–2010: findings from the global of! 40 percent of people who take statins actual statin use was defined as the presence of any relevant code the., Zatko D, Harshfield a, et al or stroke in sweden doses. By reading our Privacy Policy the prescription data available at www.heart.org/corporatefunding the quality of therapy.

Danby Silhouette Beverage Cooler, Concern Quotes For Her, Northwest University Canada, Nancy Gates Uta, Camp Lake Middle Sister,